Evaluation in human cadaveric models confirmed compatibility after insertion using an endoscopic-assisted craniotomy surgery, ease of array positioning, and robustness and reliability of the soft electrodes. Experiments in mice demonstrated that these implants reliably evoked auditory neural activity over 1 month in vivo. We fabricated soft ABIs to the scale of mouse and human CN and validated them in vitro. The soft ABI array design relies on precise microstructuring of plastic-metal-plastic multilayers to enable mechanical compliance, patterning, and electrical function. We developed implantable ABIs that are compatible with surgical handling, conform to the curvature of the CN after placement, and deliver efficient electrical stimulation. Here, we hypothesized that a soft ABI could enhance biomechanical compatibility with the curved CN surface.
The complex anatomy and physiology of the CN, together with poor spatial selectivity of electrical stimulation and inherent stiffness of contemporary multichannel arrays, leads to only modest auditory outcomes among ABI users. The ABI electrode array rests on the surface of the cochlear nucleus (CN) in the brainstem and delivers multichannel electrical stimulation. However, more prospective studies are needed to confirm and further explore this potential.Auditory brainstem implants (ABIs) provide sound awareness to deaf individuals who are not candidates for the cochlear implant. Conclusions: Brainstem implantation has the potential to improve self-reported hearing ability, hearing-related quality of life, and reduce tinnitus in NF2 patients. An increase in tinnitus severity from 26 to 84 points in THI was observed in the remaining patient, who had the greatest intensity of NF2 symptoms in the postoperative period and reported the smallest benefits with ABI. Patients and was reduced in one patient (mean improvement in THI score for these patients of M = 25 SD = 21). Score of M = 38 SD = 13), which was most pronounced for basic and advanced sound perception. A considerable improvement was also noted in the patients’ hearing-related quality of life (mean improvement in NCIQ Based on the self-reported results, it was found thatĮach patient noticed an improvement in hearing ability (mean improvement in APHAB score of M = 25 SD = 27), which was greatest in background noise conditions. (APHAB) was used to evaluate self-perceived hearing ability and Nijmegen Cochlear Implant Questionnaire (NCIQ) to assess Results: Of the 6 patients who initially agreed to participate, 4 returned questionnaires. The Abbreviated Profile of Hearing Aid Benefit
#AUDITORY BRAINSTEM IMPLANT SERIES#
A series of 6 patients who underwent ABI in a single tertiary referral center wereĪsked to fill in two sets of questionnaires referring to their pre- and postoperative experiences. Material and Methods: The study was a retrospective design. This study evaluated the self-reported hearing ability, hearing-related quality of life, and tinnitus severity in 4 adult ABI users.
One of the co-occurring symptoms in these patients is tinnitus however, little is known about its prevalenceĪnd severity. Background: Auditory brainstem implantation (ABI) is a modern method of treating hearing impairment, directed especially to patients with
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